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doi:10.1200/JCO.2017.77.4414 Uhelski ACR, Blackford AL, Sheng JY

46, 47 Knock out (/) of the AT 1a receptor gene decreased baseline blood pressure 46, 48 and abolished the pressor response to Ang II infusion, 46, 49 whereas deletion of AT 1b genes did not alter baseline blood pressure, nor the pressor response to Ang II

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